Ankylosing Spondylitis: Causes, Symptoms & Treatment

Causes of Ankylosing Spondylitis

Exact Cause of Ankylosing Spondylitis is not fully known. But it causes due to a particular gene. It is closely linked with conditions HLA-B27. In research, Conclusions are made that person suffering from Ankylosing Spondylitis carry a particular gene called as human leukocyte antigen B27 (HLA-B27).Four out of Five people suffering from Ankylosing Spondylitis have (HLA_B27).Some people have (HLA-B27) in their gene but are not suffering from Ankylosing Spondylitis. So it totally depends on health conditions of a person whether he will be suffering from Ankylosing Spondylitis or not.

Symptoms of Ankylosing Spondylitis

Ankylosing Spondylitis is caused mainly in 0.1% to 0.5% of adult populations i.e. from 17 years of age. Ankylosing Spondylitis mainly affects in spine


InAnkylosing Spondylitis person suffers stiffness in low back hip and buttocks. It starts mainly from sacroiliac joints. In a lower back region where sacrum (lower part of the spine) is present which joins with Ilium bone of the pelvis.


In Lower back region and buttocks there is an excessive pain while walking, sitting and also for day to day work. Spondylitis also may affect some of the ligaments and tendons that attach to bones. So there is a pain in ligaments and tendons.

Bony Fusion:

In Ankylosing spondylitis there is an overgrowth of bones which causes “Bony fusion”.Fusion of the ribs to the spine or breastbone may limit a person’s ability to expand his or her chest when taking a deep breath

Treatment for Ankylosing Spondylitis

Ankylosing Spondylitis is a chronic inflammatory disease involving mainly axial skeleton and also peripheral joints at the anomitical level the diseases mainly starts with inflammation vertebral column which results in the formation of inflammatory scars which finally fuse or calcify the vertebral column.
This is an extremely painful condition and further progression of diseases adds to the gradual limitation of movements, increases in pain. Even performing daily activities becomes a hard & painful task for a patient suffering from A.S. The further degeneration of diseases involves other vital organs like eyes, heart, and lungs.
Medical Science has not yet pointed as a specific cause of Ankylosing Spondylitis till now. However, HLA B27 is a gene has been associated with A.S nor have present day medical science provided any treatment for Ankylosing Spondylitis. However, the good news is that we have a very promising and fully practically proven treatment is a form of stem cell –“Future of Medicine” as we say. Stem cell after transplanting in body differentiates into the immune cell and correct the immunity system not only this but also being characterized unique property of regeneration. They damaged the tissue. This treatment of MSC (mysylecamel stem cell) not only halts the progression of diseases but also reverse certain spine condition towards normal.


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