Ankylosing Spondylitis : Evidence of improvement with stem cell Treatment | Recent case study

Patient’s Treatment Timeline :


A 39 years male patient was admitted our hospital for treatment of Ankylosing Spondylitis diagnosed 6 years back; with C/O Pain in Hip Joint & back increased since 6 months, occasional knee pain & numbness in all extremities.

Physical Examination: Stiffness and restricted movements in cervical & lumbar spine.

Pathological Findings: ANA & HLAB27 Positive

The Plan of Treatment:

  1. Autologus Mesenchymal Stem Cell Transplant with Stromal factor

Bone Marrow & Adipose Tissue derived Mecenchymal Stem Cells with Stromal factor was transplanted through intravenous transplant.

As the Ankylosing Spondylitis is a auto immune disorder in which inflammation causes tissue damage, Stem Cell transplant helps by immunomodulatory & anti inflammatory action.

  1. Supplementation of deficient vitamins like D3, B12 and minerals like zinc, calcium; amino acids like glutathyon, argenine and proteins so as to maintain the micro environment needed for stem cell to differentiate and maintain the potency.
  2. Physiotherapy exercise & Acupuncture Therapy as per Chinese Traditional Method


The patient is recovering well with 40 % increased mobility and flexibility without pain.  The confidence level is increased.

Further two sessions of transplant is planned in next six months.

Stem Cell Treatment Procedure

Step 1

Patient Evaluation + Diagnostic Investigations

Step 2

Aspiration of Stem Cells from Bone Marrow and Adipose Tissues

Step 3

Processing of Stem Cells in Tissue Culture Laboratory

Step 4

Transplantation of stem cells

Step 5

Application of Allied Therapies

Stem Cell Treatment have shown wonderful improvements in Ankylosing Spondylitis. This treatment is available at our all centers in Mumbai and Benglore. After this treatment almost all our AS patients are now is good condition and enjoying there life to fullest.




Intravenous administration of mesenchymal stem cells derived from bone marrow after contusive spinal cord injury improves functional outcome.

Transplantation of mesenchymal stem cells (MSCs) derived from bone marrow has been shown to improve functional outcome in spinal cord injury (SCI). Systemic and intrathecal delivery of MSCs results in therapeutic benefits in a number of experimental central nervous system disorders.

In the present study we transplanted MSCs derived from bone marrow through Lumbar Puncture at various time intervals after transplantation of a severe contusive SCI to study their therapeutic effects. MSCs were systemically delivered at varied time intervals (6h to 28 days after SCI).

The availability of autologous MSCs in large number and the potential for systemically delivering cells to target lesion areas without neurosurgical intervention suggests the potential utility of intravenous cell delivery as a prospective therapeutic approach in acute and subacute SCI.